Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.53 |
| ▸ | ACLY | P53396 | 3/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28415837 | 0.91 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL28414561 | 0.90 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL28412987 | 0.90 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL28410119 | 0.88 | SLC40A1 (0.52) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL28418717 | 0.87 | STAT3 (0.72) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL28410206 | 0.85 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL28418715 | 0.83 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL2120606 | 0.78 | ACLY (0.54) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL28422420 | 0.77 | TUBB4A (0.42) | TUBB4ATUBBTUBA3CSTAT3TUBA1B | |
| SCHEMBL15637592 | 0.71 | CYP11B2 (0.61) | EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320575-B | Pyridine-2-aryl-3-sulfonamide compound and synthesis method and application thereof | 浙江大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-111320575-A | Pyridine-2-aryl-3-sulfonamide compound and synthesis method and application thereof | 浙江大学 | 2020-06-23 | — | — | CN | disclosed |