SCHEMBL2841309

SCHEMBL2841309

O=S(=O)(O)c1ccc(Cl)cc1-c1cc(Cl)ccc1S(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.48
TRPV4 Q9HBA0 1/20 0.41
HSP90AA1 P07900 1/20 0.41
GRIK1 P39086 1/20 0.41
GRIK2 Q13002 1/20 0.41
TGM2 P21980 1/20 0.39
CES1 P23141 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
PPOX P50336 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TET2 Q6N021 1/20 0.38
ITGA1 P56199 2/20 0.37
MAPK1 P28482 1/20 0.37
CYP2C9 P11712 1/20 0.37
DDR1 Q08345 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7173896 0.88 S100A4 (0.42) S100A4TRPV4HSP90AA1GRIK1GRIK2
SCHEMBL8178017 0.85 PTGDR2 (0.46) S100A4HSP90AA1GRIK1GRIK2ITGA1
SCHEMBL4905860 0.83 LMNA (0.39) S100A4HSP90AA1ALDH1A1MAPK1
SCHEMBL196568 0.82 S100A4 (0.48) S100A4TRPV4HSP90AA1GRIK1GRIK2
SCHEMBL1729184 0.82 HSD11B1 (0.45) TRPV4GRIK1GRIK2TP53ITGA1
SCHEMBL30678861 0.82 HSD11B1 (0.45) TRPV4GRIK1GRIK2TP53ITGA1
SCHEMBL6915374 0.80 HSD11B1 (0.44) TRPV4GRIK1GRIK2TP53ITGA1
SCHEMBL4301050 0.80 S100A4 (0.46) S100A4TRPV4HSP90AA1GRIK1GRIK2
SCHEMBL8720622 0.80 HSD11B1 (0.44) TRPV4GRIK1GRIK2TP53ITGA1
Ammonia Solution, Strong SCHEMBL3146905 0.80 HSD11B1 (0.44) TRPV4GRIK1GRIK2TP53ITGA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120251919-A1 POLYARYLENE-BASED COPOLYMER AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
EP-2489690-A1 POLYARYLENE COPOLYMER AND USES THEREOF Sumitomo Chemical Company Limited (JP) 2012-08-22 EP disclosed
US-20100129729-A1 CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-05-27 US disclosed
EP-2147943-A1 CROSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE, CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL Sumitomo Chemical Company, Limited (JP) 2010-01-27 EP disclosed
US-20090253015-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2009-10-08 US disclosed
EP-1857482-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-11-21 EP disclosed