SCHEMBL196568

SCHEMBL196568

O=S(=O)(O)c1cc(Cl)ccc1-c1ccc(Cl)cc1S(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 2/20 0.48
HSP90AA1 P07900 1/20 0.41
MCL1 Q07820 3/20 0.40
ALDH1A1 P00352 3/20 0.40
CES1 P23141 1/20 0.39
NSD2 O96028 1/20 0.39
MMP14 P50281 1/20 0.39
CASP6 P55212 1/20 0.39
TSHR P16473 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
TP53 P04637 1/20 0.39
PPOX P50336 1/20 0.39
GRIK1 P39086 1/20 0.38
GRIK2 Q13002 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TRPV4 Q9HBA0 1/20 0.37
METAP1 P53582 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3696775 0.98 S100A4 (0.46) S100A4HSP90AA1MCL1ALDH1A1CES1
SCHEMBL3695968 0.98 S100A4 (0.46) S100A4HSP90AA1MCL1ALDH1A1CES1
SCHEMBL3699050 0.98 S100A4 (0.46) S100A4HSP90AA1MCL1ALDH1A1CES1
SCHEMBL4301050 0.98 S100A4 (0.46) S100A4HSP90AA1MCL1ALDH1A1CES1
SCHEMBL2742906 0.88 S100A4 (0.42) S100A4HSP90AA1MCL1ALDH1A1ALOX15
SCHEMBL6562906 0.85 ACLY (0.47) S100A4HSP90AA1
Hydrochloric Acid SCHEMBL2766272 0.83 ACLY (0.46) S100A4HSP90AA1
SCHEMBL29384019 0.82 MCL1 (0.53) MCL1ALDH1A1TSHRL3MBTL1HPGD
SCHEMBL198460 0.82 MCL1 (0.53) MCL1ALDH1A1TSHRL3MBTL1HPGD
SCHEMBL2841309 0.82 S100A4 (0.48) S100A4HSP90AA1ALDH1A1CES1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460789-B1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-04-19 EP disclosed
EP-2519554-B1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING DU PONT (US) 2016-03-16 EP disclosed
US-9079830-B2 Method for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-14 US disclosed
EP-2390241-B1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-10-01 EP disclosed
US-8609804-B2 Polyarylene polymers and processes for preparing E I DU PONT DE NEMOURS AND COMPANY (US) 2013-12-17 US disclosed
US-8598349-B2 Method for manufacturing conjugated aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-03 US disclosed
US-20120322973-A1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-20 US disclosed
EP-2519554-A2 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E.I. Du Pont De Nemours And Company (US) 2012-11-07 EP disclosed
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
US-20120251919-A1 POLYARYLENE-BASED COPOLYMER AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 EP disclosed
EP-2147943-A1 CROSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE, CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL Sumitomo Chemical Company, Limited (JP) 2010-01-27 EP disclosed
US-20090326188-A1 Method for producing polyarylene SUMITOMO CHEMICAL COMPANY, LIMITED 2009-12-31 US disclosed
US-20090253015-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2009-10-08 US disclosed
EP-2065420-A1 METHOD FOR PRODUCING POLYARYLENE Sumitomo Chemical Company, Limited (JP) 2009-06-03 EP disclosed
US-20090036632-A1 Polyarylene and Process for Producing the Same SUMITOMO CHEMICAL COMPANY, LIMITED 2009-02-05 US disclosed
EP-1995265-A1 POLYARYLENE AND PROCESS FOR PRODUCING THE SAME Sumitomo Chemical Company, Limited (JP) 2008-11-26 EP disclosed
US-7375176-B2 Liquid crystal poly(phenylene sulfonic acids) CASE WESTERN RESERVE UNIVERSITY 2008-05-20 US disclosed
EP-1857482-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-11-21 EP disclosed
US-20050239994-A1 Liquid crystal poly(phenylene sulfonic acids) CASE WESTERN RESERVE UNIVERSITY 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036632-A1 Polyarylene and Process for Producing the Same CYP1A1, CYP1B1, C1R S100A4 4787/4885HSP90AA1 4392/4885MCL1 286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.