Formic Acid

Formic Acid

SCHEMBL28413481

Clc1cccc2[nH]ccc12.O=CO

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 10/20 0.51
GAA P10253 2/20 0.46
MAPT P10636 2/20 0.46
AHR P35869 1/20 0.46
DAO P14920 1/20 0.41
MAPK1 P28482 1/20 0.40
NOS1 P29475 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29557397 0.88 RHEB (0.61) RHEBGAAMAPTAHRNOS1
SCHEMBL73057 0.88 RHEB (0.61) RHEBGAAMAPTAHRNOS1
Formic Acid Methyl Ester SCHEMBL28167602 0.84 RHEB (0.50) RHEBGAAMAPTAHR
Acetic Acid SCHEMBL3362174 0.84 RHEB (0.50) RHEBGAAMAPTAHR
Tert-Butyl Formate SCHEMBL27772035 0.80 RHEB (0.47) RHEBGAAMAPTAHR
Ethoxycarbonyl Group SCHEMBL27524232 0.79 RHEB (0.46) RHEBGAAMAPTAHR
Pyridine SCHEMBL28518671 0.76 PIK3CD (0.53) RHEBGAAMAPTAHRNOS1
Pyrimidine SCHEMBL28430953 0.76 RHEB (0.50) RHEBGAAMAPTAHRNOS1
Ethane SCHEMBL28964526 0.76 RHEB (0.50) RHEBGAAMAPTAHRNOS1
Formic Acid SCHEMBL28273871 0.76 RHEB (0.49) RHEBAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107118145-B Method for cyclizing and synthesizing indole under co-catalysis of palladium-organic nitrite 中国科学技术大学 2020-05-05 CN disclosed