Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 8/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | DHPS | P49366 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557397 | 0.87 | RHEB (0.61) | RHEBGAAMAPTAHR | |
| SCHEMBL73057 | 0.87 | RHEB (0.61) | RHEBGAAMAPTAHR | |
| Formic Acid SCHEMBL28413481 | 0.84 | RHEB (0.51) | RHEBGAAMAPTAHR | |
| SCHEMBL9116039 | 0.80 | GAA (0.47) | RHEBGAAMAPTAHRFTO | |
| Formic Acid Methyl Ester SCHEMBL28167602 | 0.79 | RHEB (0.50) | RHEBGAAMAPTAHRTUBB4A | |
| N-Acetylaspartic Acid SCHEMBL3826211 | 0.79 | ITGB2 (0.43) | GAARECQL | |
| Pyridine SCHEMBL28518671 | 0.79 | PIK3CD (0.53) | RHEBGAAMAPTAHR | |
| Ethane SCHEMBL28964526 | 0.79 | RHEB (0.50) | RHEBGAAMAPTAHR | |
| Acetic Acid SCHEMBL27942674 | 0.79 | RHEB (0.45) | RHEB | |
| Ethane SCHEMBL28964522 | 0.77 | RHEB (0.49) | RHEBGAAMAPTAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107365822-A | A kind of preparation method of olive growing leaves protein extract | 安徽华健生物科技有限公司 | 2017-11-21 | — | — | CN | claimed |
| CN-102348385-A | Method for recovering male sterility of gramineous plants and male sterility recovering agent | UNIV TOHOKU | 2012-02-08 | — | — | CN | claimed |
| CN-101690485-A | Preparation for reducing the nitrate content of leafy vegetables | NORTHWESTAGRICULTURE AND FORES | 2010-04-07 | — | — | CN | claimed |
| CN-100389648-C | Method for preparing orchid haploid by treating orchid non-pollen with auxin and method for culturing orchid | SAPPORO BREWERIES (JP) | 2008-05-28 | — | — | CN | claimed |
| CN-1697605-A | Method for preparing orchid haploid by treating orchid non-pollen with auxin and method for culturing orchid | SAPPORO BREWERIES (JP) | 2005-11-16 | — | — | CN | claimed |
| CN-1157117-C | Plant growth regulating composition having resisting and growth promoting function | 四川龙蟒福生科技有限责任公司 | 2004-07-14 | — | — | CN | claimed |
| CN-1377578-A | Plant growth regulating composition having resisting and growth promoting function | LONGMANG FUSHENG SCIENCE AND T (CN) | 2002-11-06 | — | — | CN | claimed |
| US-5244794-A | Flavor compounds from allium root cultures | CORNELL RESEARCH FOUNDATION, INC. (US) | 1993-09-14 | — | — | US | claimed |
| CN-107365822-A | A kind of preparation method of olive growing leaves protein extract | 安徽华健生物科技有限公司 | 2017-11-21 | — | — | CN | disclosed |
| CN-103621505-A | Application of halogenated indole-3-acetic acid as herbicide | UNIV SOUTHEAST | 2014-03-12 | — | — | CN | disclosed |
| CN-103502204-A | Auxin biosynthesis inhibitor | RIKEN | 2014-01-08 | — | — | CN | disclosed |
| CN-102702565-B | Preparation method and application of indole acetic acid (IAA) molecularly imprinted polymer (MIP) | UNIV FUZHOU | 2013-12-04 | — | — | CN | disclosed |
| US-8486863-B2 | Activators of lateral root formation | VIB VZW (BE) | 2013-07-16 | — | — | US | disclosed |
| CN-101690485-B | Preparation for reducing the nitrate content of leafy vegetables | UNIV NORTHWEST A&F | 2012-10-24 | — | — | CN | disclosed |
| CN-100389648-C | Method for preparing orchid haploid by treating orchid non-pollen with auxin and method for culturing orchid | SAPPORO BREWERIES (JP) | 2008-05-28 | — | — | CN | disclosed |
| CN-1697605-A | Method for preparing orchid haploid by treating orchid non-pollen with auxin and method for culturing orchid | SAPPORO BREWERIES (JP) | 2005-11-16 | — | — | CN | disclosed |
| CN-1157117-C | Plant growth regulating composition having resisting and growth promoting function | 四川龙蟒福生科技有限责任公司 | 2004-07-14 | — | — | CN | disclosed |
| CN-1157117-C | Plant growth regulating composition having resisting and growth promoting function | 四川龙蟒福生科技有限责任公司 | 2004-07-14 | — | — | CN | disclosed |
| CN-1377578-A | Plant growth regulating composition having resisting and growth promoting function | LONGMANG FUSHENG SCIENCE AND T (CN) | 2002-11-06 | — | — | CN | disclosed |
| WO-1995034658-A1 | MICROBIAL PRODUCTION OF INDOLE-3-ACETIC ACIDS AND SUBSTITUTED ANALOGS THEREOF VIA FERMENTATION | GENENCOR INTERNATIONAL, INC. (US) | 1995-12-21 | — | — | WO | disclosed |