Pyridine

Pyridine

SCHEMBL28518671

Clc1cccc2[nH]ccc12.c1ccncc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 2/20 0.53
RHEB Q15382 10/20 0.50
AHR P35869 1/20 0.44
NOS1 P29475 1/20 0.42
AXL P30530 1/20 0.42
PRKCI P41743 1/20 0.42
PIK3CB P42338 1/20 0.39
PIK3CG P48736 1/20 0.39
GAA P10253 2/20 0.39
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimidine SCHEMBL28430953 0.89 RHEB (0.50) PIK3CDRHEBAHRNOS1AXL
SCHEMBL29557397 0.87 RHEB (0.61) PIK3CDRHEBAHRNOS1GAA
SCHEMBL73057 0.87 RHEB (0.61) PIK3CDRHEBAHRNOS1GAA
Acetic Acid SCHEMBL3362174 0.79 RHEB (0.50) RHEBAHRGAAMAPT
Pyridine SCHEMBL28523843 0.79 PIK3CD (0.53) PIK3CDRHEBAHRPIK3CBPIK3CG
Pyridine SCHEMBL28520362 0.79 PIK3CD (0.53) PIK3CDRHEBAHRPIK3CBPIK3CG
Formic Acid SCHEMBL28413481 0.76 RHEB (0.51) RHEBAHRNOS1GAAMAPT
Ethane SCHEMBL28964526 0.75 RHEB (0.50) RHEBAHRNOS1GAAMAPT
Pyridine SCHEMBL9319094 0.75 PIK3CD (0.49) PIK3CDAHR
Ethane SCHEMBL28964522 0.74 RHEB (0.49) RHEBAHRGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112209915-A Method for air oxidation of N-pyridine indoline compounds 宁波大学 2021-01-12 CN disclosed