SCHEMBL73057

SCHEMBL73057

Clc1cccc2[nH]ccc12

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 11/20 0.61
AHR P35869 2/20 0.56
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
NOS1 P29475 1/20 0.47
PIK3CD O00329 1/20 0.46
GAA P10253 2/20 0.45
MAPT P10636 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29557397 1.00 RHEB (0.61) RHEBAHRCYP1A2CYP2A6NOS1
Formic Acid SCHEMBL28413481 0.88 RHEB (0.51) RHEBAHRNOS1GAAMAPT
Pyridine SCHEMBL28518671 0.87 PIK3CD (0.53) RHEBAHRNOS1PIK3CDGAA
Acetic Acid SCHEMBL3362174 0.87 RHEB (0.50) RHEBAHRGAAMAPT
Pyrimidine SCHEMBL28430953 0.87 RHEB (0.50) RHEBAHRNOS1PIK3CDGAA
Ethane SCHEMBL28964526 0.87 RHEB (0.50) RHEBAHRNOS1GAAMAPT
Ethane SCHEMBL28964522 0.85 RHEB (0.49) RHEBAHRGAAMAPT
Formic Acid Methyl Ester SCHEMBL28167602 0.84 RHEB (0.50) RHEBAHRGAAMAPT
SCHEMBL8192772 0.82 AHR (0.68) RHEBAHR
SCHEMBL6321487 0.81 RHEB (0.57) RHEBAHRPIK3CDGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 961 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4526426-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS Danmarks Tekniske Universitet (DK) 2025-03-26 EP claimed
CN-118125960-A Bisindole 3-ketone compound, application and preparation method thereof 云南农业大学 2024-06-04 CN claimed
WO-2023222879-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS DANMARKS TEKNISKE UNIVERSITET (DK) 2023-11-23 WO claimed
CN-114394963-B Isoxazoline compound, preparation method and application 西北农林科技大学 2023-05-23 CN claimed
CN-114805664-B Bionic modified marine antifouling resin material, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2023-04-14 CN claimed
CN-115232052-A Tetraindolylmethane compound and preparation method and application thereof 南京工业大学 2022-10-25 CN claimed
CN-112574093-B Novel green method for preparing 3-diaryl methyl substituted indole compound 湖南理工学院 2022-10-04 CN claimed
CN-114805664-A Bionic modified marine antifouling resin material, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2022-07-29 CN claimed
CN-114292582-B Hyperbranched coating suitable for marine concrete, and preparation method and application thereof 江苏苏博特新材料股份有限公司 2022-07-12 CN claimed
CN-114539080-A Preparation method of 2- (2-amino-6-chlorphenyl) -sodium acetate 八叶草健康产业研究院(厦门)有限公司 2022-05-27 CN claimed
US-20050075242-A1 Heterocyclic nitrogen-containing activators and catalyst systems for olefin polymerization UNIVATION TECHNOLOGIES, LLC 2005-04-07 US claimed
EP-1517931-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION Univation Technologies, LLC (US) 2005-03-30 EP claimed
EP-1517932-A2 HETEROCYCLIC NITROGEN-CONTAINING ACTIVATORS AND CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION Univation Technologies LLC (US) 2005-03-30 EP claimed
US-20040127348-A1 Halogen substituted catalyst system for olefin polymerization UNIVATION TECHNOLOGIES, LLC 2004-07-01 US claimed
WO-2004003037-A1 HALOGEN SUBSTITUTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC. (US) 2004-01-08 WO claimed
WO-2004003032-A2 HETEROCYCLIC NITROGEN-CONTAINING ACTIVATORS AND CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC (US) 2004-01-08 WO claimed
EP-0954596-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES PHYTON, INC. (US) 1999-11-10 EP claimed
WO-1997044476-A1 ENHANCED PRODUCTION OF TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON, INC. (US) 1997-11-27 WO claimed
EP-0076713-B1 AMINOMETHYL-1H-INDOLE-4-METHANOL DERIVATIVES AND THEIR SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1986-01-08 EP claimed
EP-0076713-A1 Aminomethyl-1H-indole-4-methanol derivatives and their salts, process and intermediates for their preparation, their use as medicines and compositions containing them ROUSSEL-UCLAF (FR) 1983-04-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050075242-A1 Heterocyclic nitrogen-containing activators and catalyst systems for olefin polymerization NBAS, NIT2, MYB RHEB 1551/4885AHR 164/4885CYP1A2 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.