SCHEMBL29557397

SCHEMBL29557397

Clc1cccc2[nH]ccc12

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RHEB Q15382 11/20 0.61
AHR P35869 2/20 0.56
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
NOS1 P29475 1/20 0.47
PIK3CD O00329 1/20 0.46
GAA P10253 2/20 0.45
MAPT P10636 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL73057 1.00 RHEB (0.61) RHEBAHRCYP1A2CYP2A6NOS1
Formic Acid SCHEMBL28413481 0.88 RHEB (0.51) RHEBAHRNOS1GAAMAPT
Pyridine SCHEMBL28518671 0.87 PIK3CD (0.53) RHEBAHRNOS1PIK3CDGAA
Acetic Acid SCHEMBL3362174 0.87 RHEB (0.50) RHEBAHRGAAMAPT
Pyrimidine SCHEMBL28430953 0.87 RHEB (0.50) RHEBAHRNOS1PIK3CDGAA
Ethane SCHEMBL28964526 0.87 RHEB (0.50) RHEBAHRNOS1GAAMAPT
Ethane SCHEMBL28964522 0.85 RHEB (0.49) RHEBAHRGAAMAPT
Formic Acid Methyl Ester SCHEMBL28167602 0.84 RHEB (0.50) RHEBAHRGAAMAPT
SCHEMBL8192772 0.82 AHR (0.68) RHEBAHR
SCHEMBL6321487 0.81 RHEB (0.57) RHEBAHRPIK3CDGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263760-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-08-21 US disclosed
EP-4526426-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS Danmarks Tekniske Universitet (DK) 2025-03-26 EP disclosed
EP-4426676-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-09-11 EP disclosed
WO-2023081837-A9 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-03-14 WO disclosed
WO-2023242462-A1 COMPOSITION AND METHOD FOR COATING SEEDS CO2 REVOLUTION, S.L. (ES) 2023-12-21 WO disclosed
WO-2023222879-A2 METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS DANMARKS TEKNISKE UNIVERSITET (DK) 2023-11-23 WO disclosed
CN-114573496-B Preparation method of 4-chloroindole-3-acetic acid 贵州大学 2023-11-07 CN disclosed
WO-2023081837-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2023-05-11 WO disclosed
EP-4165037-A1 ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS Aligos Therapeutics, Inc. (US) 2023-04-19 EP disclosed
CN-114573496-A Preparation method of 4-chloroindole-3-acetic acid 贵州大学 2022-06-03 CN disclosed
CN-114539080-A Preparation method of 2- (2-amino-6-chlorphenyl) -sodium acetate 八叶草健康产业研究院(厦门)有限公司 2022-05-27 CN disclosed