Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CRHBP | P24387 | 2/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338806 | 0.86 | TSHR (0.44) | MAOAMAOBTSHRABCG2ITGB2 | |
| SCHEMBL23362988 | 0.77 | MAOA (0.38) | MAOAMAOBTSHRABCG2ITGB2 | |
| SCHEMBL14591135 | 0.77 | MAOA (0.38) | MAOAMAOBTSHRABCG2ITGB2 | |
| SCHEMBL22439186 | 0.77 | MAOA (0.38) | MAOAMAOBTSHRABCG2ITGB2 | |
| SCHEMBL19859855 | 0.75 | — | — | |
| SCHEMBL533876 | 0.70 | CHRNB2 (0.33) | CA2 | |
| SCHEMBL2122942 | 0.70 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL20721930 | 0.70 | AHR (0.40) | NPSR1HTR2CSMN1; SMN2HTT | |
| SCHEMBL2119376 | 0.70 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL1924724 | 0.70 | DRD2 (0.38) | HTR2CCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2145 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063326-A | Method for promoting nickel catalysis to synthesize arylamine compound by red light | 陕西师范大学 | 2024-05-24 | — | — | CN | claimed |
| EP-4357351-A1 | TRAP1 INHIBITOR AND USE THEREOF | Smartin Bio Inc. (KR) | 2024-04-24 | — | — | EP | claimed |
| US-20240122941-A1 | THERAPY BASED ON SYNTHETIC LETHALITY IN SWI/SNF COMPLEX-DYSFUNCTION CANCER | NATIONAL CANCER CENTER (JP) | 2024-04-18 | — | — | US | claimed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117769559-A | TRAP1 inhibitors and uses thereof | 斯玛特恩生物公司 | 2024-03-26 | — | — | CN | claimed |
| WO-2023148206-A1 | MICROBIOCIDAL N-AMIDE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-10 | — | — | WO | claimed |
| US-11572384-B2 | Unusual substrates of tubulin tyrosine ligase | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2023-02-07 | — | — | US | claimed |
| US-11535647-B2 | Peptide purification method using sulfonate compound | NAGASE & CO., LTD. (JP) | 2022-12-27 | — | — | US | claimed |
| WO-2022265178-A1 | TRAP1 INHIBITOR AND USE THEREOF | 주식회사 스마틴바이오 | 2022-12-22 | — | — | WO | claimed |
| CN-109923116-B | [1,2,4] triazolo [1,5-a ] pyrimidine derivatives as PDE2 inhibitors | 詹森药业有限公司 | 2022-12-06 | — | — | CN | claimed |
| US-5478857-A | Administering inhibitor of phospholipase A2 | ELI LILLY AND COMPANY (US) | 1995-12-26 | — | — | US | claimed |
| EP-0685466-A1 | 3-Heteroaliphatyle-and 3-hetero-(aryle)-aliphatyle-2(1H)-quinolone derivatives | CIBA-GEIGY AG (CH) | 1995-12-06 | — | — | EP | claimed |
| WO-1995017183-A1 | USE OF PLA2 INHIBITORS AS TREATMENT FOR ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 1995-06-29 | — | — | WO | claimed |
| EP-0406438-B1 | PRODUCTION OF GLYCIDYL ETHER | KOWA CO (JP) | 1994-03-16 | — | — | EP | claimed |
| US-4997836-A | Inhibitor of platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-03-05 | — | — | US | claimed |
| US-4939128-A | Antiischemic agents; circulatory disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-07-03 | — | — | US | claimed |
| EP-0100200-B1 | 2-SUBSTITUTED 4-AMINO-6,7-DIMETHOXYQUINOLINES | Pfizer Limited (GB) | 1987-05-06 | — | — | EP | claimed |
| US-4656174-A | HYPOTENSIVE AGENTS | PFIZER INC. (US) | 1987-04-07 | — | — | US | claimed |
| EP-0202589-A2 | Pharmaceutical compositions containing ascorbic acid derivatives | Takeda Chemical Industries, Ltd. (JP) | 1986-11-26 | — | — | EP | claimed |
| EP-0100200-A1 | 2-Substituted 4-amino-6,7-dimethoxyquinolines | Pfizer Limited (GB) | 1984-02-08 | — | — | EP | claimed |