Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28084227 | 0.79 | KMT2A (0.46) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL7402520 | 0.75 | CA12 (0.53) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL12834642 | 0.75 | CYP1A2 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL22649171 | 0.75 | CYP1A2 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8898810 | 0.74 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL8897056 | 0.74 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL11656910 | 0.74 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL30660067 | 0.72 | MEN1 (0.50) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8011548 | 0.72 | MEN1 (0.50) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL1286243 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPTRAB9ANPSR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138506-B | Preparation method of isepamicin sulfate | 浙江弘盛药业有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-111138506-A | Preparation method of isepamicin sulfate | 浙江弘盛药业有限公司 | 2020-05-12 | — | — | CN | claimed |
| CN-111138506-B | Preparation method of isepamicin sulfate | 浙江弘盛药业有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-111138506-A | Preparation method of isepamicin sulfate | 浙江弘盛药业有限公司 | 2020-05-12 | — | — | CN | disclosed |