SCHEMBL284164

SCHEMBL284164

COC(=O)CSSCC(=O)OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
HSD17B10 Q99714 4/20 0.48
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
POLB P06746 2/20 0.39
KMT2A Q03164 2/20 0.39
TET2 Q6N021 1/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7115937 0.86
SCHEMBL13563292 0.85 TSHR (0.42) TSHRHSD17B10MGAMGAASI
SCHEMBL4071858 0.85 TSHR (0.40) TSHRHSD17B10MGAMGAASI
SCHEMBL13563259 0.84
SCHEMBL11056301 0.81 TSHR (0.53) TSHRHSD17B10MGAMGAASI
SCHEMBL9595662 0.80 TSHR (0.40) TSHRHSD17B10MGAMGAASI
SCHEMBL30888816 0.79 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL1780903 0.79
SCHEMBL7113341 0.78 TSHR (0.34) TSHRHSD17B10MGAMGAASI
SCHEMBL18312079 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022080409-A1 ESTER COMPOUND, METHOD FOR SYNTHESIZING ESTER COMPOUND, AND RESIN COMPOSITION 昭和電工マテリアルズ株式会社 2022-04-21 WO claimed
US-10124056-B2 Alkylated influenza vaccines SANOFI PASTEUR INC. (US) 2018-11-13 US claimed
EP-3182998-A1 ALKYLATED INFLUENZA VACCINES Sanofi Pasteur Inc. (US) 2017-06-28 EP claimed
WO-2016028776-A1 ALKYLATED INFLUENZA VACCINES SANOFI PASTEUR BIOLOGICS LLC (US) 2016-02-25 WO claimed
US-20160045590-A1 ALKYLATED INFLUENZA VACCINES SANOFI PASTEUR INC. 2016-02-18 US claimed
US-8592356-B2 Lubricant composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2013-11-26 US claimed
US-8309499-B2 Lubricant composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2012-11-13 US claimed
US-20120238481-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2012-09-20 US claimed
US-20230318033-A1 ADDITIVE, AND LITHIUM SECONDARY BATTERY ELECTROLYTE AND LITHIUM BATTERY WHICH COMPRISE SAME SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION (KR) 2023-10-05 US disclosed
CN-115572380-B Degradable polyester, preparation method thereof, degradation method and application 中国科学院宁波材料技术与工程研究所 2023-09-19 CN disclosed
US-20230213857-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING RADICAL TRAPPING AGENT NISSAN CHEMICAL CORPORATION (JP) 2023-07-06 US disclosed
US-20230151054-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES Universität Heidelberg (DE) 2023-05-18 US disclosed
US-20230151054-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES Universität Heidelberg (DE) 2023-05-18 US disclosed
CN-115572380-A Degradable polyester and preparation method, degradation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-01-06 CN disclosed
US-4203896-A WITH MERCURIC ACETATE AND ACETIC ACID, ACIDIC HYDROLYSIS OF N-PROPENYL GROUP ELI LILLY AND COMPANY (US) 1980-05-20 US disclosed
US-4144232-A Substituted azetidin-2-one antibiotics ELI LILLY AND COMPANY (US) 1979-03-13 US disclosed
US-4071682-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1978-01-31 US disclosed
US-3976769-A INSECTICIDE AIRWICK INDUSTRIES, INC. (US) 1976-08-24 US disclosed
US-3962214-A Process for preparing amino substituted β-lactam antibiotics ELI LILLY AND COMPANY (US) 1976-06-08 US disclosed
US-3954731-A Process for preparing 6-alkoxypenicillanic and 7-alkoxycephalosporin acids ELI LILLY AND COMPANY (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230318033-A1 ADDITIVE, AND LITHIUM SECONDARY BATTERY ELECTROLYTE AND LITHIUM BATTERY WHICH COMPRISE SAME SETDB1, ASH2L, LEF1 TSHR 4309/4885HSD17B10 407/4885MGAM 2001/4885
US-20230151054-A1 SULFUR EXTRUSION FROM DISULFIDES BY CARBENES TST, CBS, CTH TSHR 3757/4885HSD17B10 884/4885MGAM 3960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.