SCHEMBL28416697

SCHEMBL28416697

c1cccc(-c2ccccccns2)sncc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42
PI4KA P42356 1/20 0.42
PI4K2B Q8TCG2 1/20 0.42
PI4K2A Q9BTU6 1/20 0.42
PI4KB Q9UBF8 1/20 0.42
KDM4E B2RXH2 5/20 0.37
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
MAPT P10636 2/20 0.37
GLA P06280 1/20 0.37
TDO2 P48775 1/20 0.37
EP300 Q09472 1/20 0.35
KAT2B Q92831 1/20 0.35
KAT5 Q92993 1/20 0.35
LMNA P02545 2/20 0.33
P4HTM Q9NXG6 2/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12647822 0.74 LMNA (0.35) KDM4ENPC1RAB9AMAPTGLA
SCHEMBL6422894 0.74 CYP3A4 (0.47) NPC1RAB9AMAPTTDO2EP300
SCHEMBL3182746 0.70
Biphenyl SCHEMBL28756440 0.63 NOTUM (0.46) NPC1RAB9AMAPTTDO2LMNA
2-Aminopyridine SCHEMBL10923877 0.63 NOS3 (0.94) NOS3NOS1NOS2PI4KAPI4K2B
SCHEMBL20994044 0.61
SCHEMBL29726022 0.61
Biphenyl SCHEMBL27478909 0.61 ALDH1A1 (0.60) NPC1RAB9ACYP1A2NOTUMATM
2-Aminopyridine SCHEMBL2775240 0.59
2-Aminopyridine SCHEMBL9064720 0.59 NOS3 (1.00) NOS3NOS1NOS2PI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111200934-A Novel agrochemical pesticide composition 巴斯夫欧洲公司 2020-05-26 CN disclosed