Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 5/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 9/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30133733 | 0.78 | HTR4 (0.36) | PDK1HTR4DRD4DRD2HRH3 | |
| SCHEMBL29233712 | 0.78 | PDK1 (0.47) | PDK1HRH3 | |
| SCHEMBL28515787 | 0.75 | PDK1 (0.39) | PDK1DRD4 | |
| SCHEMBL28414511 | 0.73 | PDK1 (0.38) | PDK1HRH3 | |
| SCHEMBL23241141 | 0.72 | KDM4E (0.43) | PDK1TDP1 | |
| SCHEMBL22281704 | 0.71 | DRD1 (0.44) | PDK1HTR4TDP1HRH3 | |
| SCHEMBL22281703 | 0.71 | DRD1 (0.44) | PDK1HTR4TDP1HRH3 | |
| SCHEMBL22282080 | 0.71 | DRD1 (0.44) | PDK1HTR4TDP1HRH3 | |
| SCHEMBL5150493 | 0.70 | PDK1 (0.53) | PDK1DRD4DRD2HRH3 | |
| SCHEMBL295933 | 0.70 | PDK1 (0.53) | PDK1DRD4DRD2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938068-B | N- (morpholin-2-ylmethyl) amide derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-110938068-A | N- (morpholin-2-ylmethyl) amide derivatives and their use | 广东东阳光药业有限公司 | 2020-03-31 | — | — | CN | disclosed |