Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 3/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417596 | 0.78 | HRH3 (0.44) | PDK1NPSR1HRH3 | |
| SCHEMBL16827086 | 0.77 | GBA1 (0.39) | GBA1TACR2HRH3 | |
| SCHEMBL29233712 | 0.76 | PDK1 (0.47) | PDK1NPSR1HRH3LMNAPOLB | |
| Hydrochloric Acid SCHEMBL30133735 | 0.76 | GBA1 (0.38) | GBA1TACR2HRH3 | |
| SCHEMBL28515787 | 0.76 | PDK1 (0.39) | PDK1 | |
| SCHEMBL20240302 | 0.73 | HDAC3 (0.40) | KDM4ELMNA | |
| SCHEMBL28416724 | 0.73 | PDK1 (0.40) | PDK1HRH3 | |
| SCHEMBL1501904 | 0.70 | THRB (0.35) | TACR2LMNATHRB | |
| SCHEMBL4731247 | 0.70 | SMN1; SMN2 (0.46) | GBA1TACR2OPRM1KDM4E | |
| SCHEMBL28384624 | 0.69 | OPRK1 (0.41) | GBA1TACR2OPRM1KDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938068-B | N- (morpholin-2-ylmethyl) amide derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-110938068-A | N- (morpholin-2-ylmethyl) amide derivatives and their use | 广东东阳光药业有限公司 | 2020-03-31 | — | — | CN | disclosed |