Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 5/20 | 0.35 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | DRD4 | P21917 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414511 | 0.76 | PDK1 (0.38) | PDK1 | |
| SCHEMBL21069557 | 0.76 | PDK1 (0.45) | PDK1DRD4 | |
| SCHEMBL21069378 | 0.75 | DRD4 (0.34) | PDK1MAOBDRD4 | |
| SCHEMBL29233712 | 0.75 | PDK1 (0.47) | PDK1 | |
| SCHEMBL28416724 | 0.75 | PDK1 (0.40) | PDK1DRD4 | |
| SCHEMBL28515788 | 0.73 | KDM4E (0.36) | BCHEMAOBDRD4 | |
| SCHEMBL26923812 | 0.71 | BCHE (0.41) | PDK1BCHEMAOB | |
| SCHEMBL26925497 | 0.71 | BCHE (0.41) | PDK1BCHEMAOB | |
| SCHEMBL5776673 | 0.70 | DRD4 (0.64) | DRD4 | |
| SCHEMBL21069599 | 0.70 | DRD2 (0.33) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783205-A | Compounds for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 尼坎治疗公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |