Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2839238 | 0.81 | PGR (0.32) | PGRPNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2838245 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL673153 | 0.73 | PGR (0.32) | PGR | |
| Hydrochloric Acid SCHEMBL674514 | 0.71 | PGR (0.31) | PGR | |
| Hydrochloric Acid SCHEMBL674564 | 0.71 | PGR (0.32) | PGR | |
| Hydrochloric Acid SCHEMBL29479988 | 0.70 | PNMT (0.50) | PGRPNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL618215 | 0.70 | PNMT (0.50) | PGRPNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL10513406 | 0.69 | PNMT (0.49) | PGRPNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2841028 | 0.68 | PNMT (0.30) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4393499 | 0.67 | PNMT (0.32) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2169003-B1 | THERMOPLASTIC ELASTOMER COMPOSITION | MITSUI CHEMICALS INC (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2169003-A1 | THERMOPLASTIC ELASTOMER COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2010-03-31 | — | — | EP | disclosed |