Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5211578 | 1.00 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| Ammonia Solution, Strong SCHEMBL4752940 | 1.00 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL2812477 | 0.98 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL4609969 | 0.98 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL11457463 | 0.98 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL13983961 | 0.85 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL5217865 | 0.83 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL12180935 | 0.83 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL9634783 | 0.83 | CES2 (0.55) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL3729528 | 0.83 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553629-B | Preparation method of cefuroxime sodium intermediate E-type impurity compound | 浙江永宁药业股份有限公司 | 2020-06-23 | — | — | CN | disclosed |