Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28417876 | 1.00 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| Ammonia Solution, Strong SCHEMBL5211578 | 1.00 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL2812477 | 0.98 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL4609969 | 0.98 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL11457463 | 0.98 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL13983961 | 0.85 | CES2 (0.52) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL5217865 | 0.83 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL12180935 | 0.83 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL9634783 | 0.83 | CES2 (0.55) | CES2CES1PTPN1SMN1; SMN2TDP1 | |
| SCHEMBL3729528 | 0.83 | CES2 (0.50) | CES2CES1PTPN1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117587472-A | Electroplating solution for through blind hole co-plating and application thereof and method for through blind hole co-plating of HDI board | 上海天承化学有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-106366098-A | Cefuroxime sodium compound prepared through advanced on-line process control technology and preparation thereof | 陕西顿斯制药有限公司 | 2017-02-01 | — | — | CN | claimed |
| CN-117587472-A | Electroplating solution for through blind hole co-plating and application thereof and method for through blind hole co-plating of HDI board | 上海天承化学有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-106187960-B | A kind of preparation method of 2- methoxyiminos -2- furyl acetic acid ammonium salts | 四平市精细化学品有限公司 | 2018-08-14 | — | — | CN | disclosed |
| CN-106366098-A | Cefuroxime sodium compound prepared through advanced on-line process control technology and preparation thereof | 陕西顿斯制药有限公司 | 2017-02-01 | — | — | CN | disclosed |
| CN-106187960-A | A kind of preparation method of 2 methoxyimino 2 furyl acetic acid ammonium salts | 四平市精细化学品有限公司 | 2016-12-07 | — | — | CN | disclosed |
| WO-2008155615-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEPHALOSPORIN ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2008-12-24 | — | — | WO | disclosed |
| US-20070275954-A1 | Novel Fused Heterocycles and Uses Thereof | ASTRAZENECA AB (SE) | 2007-11-29 | — | — | US | disclosed |
| EP-1751119-A1 | NOVEL FUSED HETEROCYCLES AND USES THEREOF | AstraZeneca AB (SE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005111001-A1 | NOVEL FUSED HETEROCYCLES AND USES THEREOF | ASTRAZENECA AB (SE) | 2005-11-24 | — | — | WO | disclosed |
| WO-2004050663-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFUROXIME SODIUM | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2004-06-17 | — | — | WO | disclosed |
| WO-2004041831-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFUROXIME SODIUM | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-05-21 | — | — | WO | disclosed |
| US-20040092735-A1 | Process for the preparation of cefuroxime sodium | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-05-13 | — | — | US | disclosed |
| US-4876351-A | Process for the separation of a mixture of \"syn\" and \"anti\" oxime isomers | GLAXO GROUP LIMITED (GB) | 1989-10-24 | — | — | US | disclosed |
| US-4717768-A | Process for separation of syn and anti oxime isomers of cephalosporin-compounds | GLAXO GROUP LIMITED (GB) | 1988-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092735-A1 | Process for the preparation of cefuroxime sodium | CYP2F1, CYP51A1, CYP17A1 | CES2 1088/4885CES1 113/4885PTPN1 1363/4885 |
| US-20070275954-A1 | Novel Fused Heterocycles and Uses Thereof | VIP, CCKBR, HRH2 | CES2 1687/4885CES1 1016/4885PTPN1 3794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.