Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 5/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682331 | 0.86 | TNF (0.61) | TNFPDE4ALMNACYP1A2NFKB1 | |
| SCHEMBL19210131 | 0.83 | TNF (0.56) | TNFPDE4ALMNACYP1A2NFKB1 | |
| SCHEMBL19210136 | 0.80 | TNF (0.53) | TNFPDE4ALMNACYP1A2NFKB1 | |
| SCHEMBL28870864 | 0.80 | TNF (0.43) | TNFPDE4ALMNACYP1A2NFKB1 | |
| SCHEMBL17682329 | 0.79 | PDE4A (0.47) | TNFPDE4ALMNACYP1A2NFKB1 | |
| SCHEMBL28422631 | 0.78 | TNF (0.69) | TNFPDE4ALMNACYP1A2NFKB1 | |
| SCHEMBL14639347 | 0.71 | ADORA2B (0.56) | TNFPDE4ALMNACYP1A2NFKB1 | |
| SCHEMBL17682330 | 0.69 | ALDH1A1 (0.58) | PDE4ALMNAPMP22MAPTKMT2A | |
| SCHEMBL10813975 | 0.69 | PDE4A (0.46) | PDE4ALMNACYP1A2NFKB1ACHE | |
| SCHEMBL10811527 | 0.69 | PDE4A (0.46) | PDE4ALMNACYP1A2NFKB1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233863-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-111233863-A | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-105566324-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-04-03 | — | — | CN | disclosed |