Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682331 | 0.85 | TNF (0.61) | TNFLMNAKMT2ARXFP1MAPK1 | |
| SCHEMBL28417900 | 0.80 | TNF (0.44) | TNFLMNAHTTKMT2ARXFP1 | |
| SCHEMBL28422629 | 0.79 | TNF (0.67) | TNFLMNARXFP1ADORA2BCYP1A2 | |
| SCHEMBL17682329 | 0.70 | PDE4A (0.47) | TNFLMNAKMT2ARXFP1MAPK1 | |
| SCHEMBL11321532 | 0.68 | TNF (0.66) | TNFLMNARXFP1MAPK1ADORA2B | |
| SCHEMBL17682330 | 0.67 | ALDH1A1 (0.58) | LMNAKMT2AMAPK1ALDH1A1NPSR1 | |
| SCHEMBL17626126 | 0.66 | ADORA2B (0.65) | TNFLMNARXFP1MAPK1ADORA2B | |
| SCHEMBL17682325 | 0.65 | TNF (0.80) | TNFLMNARXFP1MAPK1ADORA2B | |
| SCHEMBL17682215 | 0.63 | TNF (0.77) | TNFLMNARXFP1MAPK1ADORA2B | |
| SCHEMBL21136085 | 0.63 | CA2 (0.46) | LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233863-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |