Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PAM | P19021 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28419062 | 0.85 | KDM4E (0.59) | HTR2CLMNAKDM4EALDH1A1GABRR1 | |
| SCHEMBL7848440 | 0.85 | ALDH1A1 (0.54) | HTR2CLMNAALDH1A1DGKACYP1A2 | |
| SCHEMBL27804583 | 0.85 | KDM4E (0.62) | HTR2CLMNAKDM4EALDH1A1GABRR1 | |
| SCHEMBL15345266 | 0.85 | KDM4E (0.62) | HTR2CLMNAKDM4EALDH1A1GABRR1 | |
| SCHEMBL242588 | 0.82 | ALDH1A1 (0.68) | LMNAALDH1A1DGKACES1CES2 | |
| SCHEMBL5664524 | 0.81 | KDM4E (0.58) | HTR2CLMNAKDM4EALDH1A1GABRR1 | |
| SCHEMBL4028287 | 0.80 | — | — | |
| Fluoride SCHEMBL28138819 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1DGKACES1CES2 | |
| SCHEMBL27467140 | 0.80 | ALDH1A1 (0.65) | LMNAALDH1A1DGKACES1CES2 | |
| SCHEMBL2272513 | 0.79 | ALDH1A1 (0.52) | HTR2CLMNAALDH1A1DGKACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112043827-A | Temperature-sensitive pharmaceutical composition, transdermal preparation, and preparation method and application thereof | 复旦大学 | 2020-12-08 | — | — | CN | claimed |
| CN-111465612-A | B cell maturation antigen binding proteins | 哈普恩治疗公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-110891596-A | Antibody variable domains and antibody constructs | 希望之城 | 2020-03-17 | — | — | CN | disclosed |