Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.51 |
| ▸ | FLT3 | P36888 | 4/20 | 0.51 |
| ▸ | CSF1R | P07333 | 2/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.51 |
| ▸ | FLT4 | P35916 | 2/20 | 0.51 |
| ▸ | MET | P08581 | 7/20 | 0.49 |
| ▸ | MST1R | Q04912 | 3/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 10/20 | 0.49 |
| ▸ | KIT | P10721 | 4/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28428906 | 0.90 | PDE4A (0.49) | KDRFLT3CSF1RPDGFRBFLT4 | |
| SCHEMBL28430848 | 0.88 | KDR (0.52) | KDRFLT3CSF1RPDGFRBFLT4 | |
| SCHEMBL30646048 | 0.87 | PDGFRA (0.50) | KDRPDGFRBMETMST1RPDGFRA | |
| SCHEMBL28428914 | 0.85 | PDGFRA (0.49) | KDRPDGFRBMETMST1RPDGFRA | |
| SCHEMBL28427821 | 0.85 | MET (0.48) | KDRFLT3PDGFRBMETMST1R | |
| SCHEMBL30646019 | 0.84 | PDGFRA (0.62) | KDRPDGFRBMETMST1RPDGFRA | |
| SCHEMBL29111053 | 0.84 | PDGFRA (0.62) | KDRPDGFRBMETMST1RPDGFRA | |
| SCHEMBL28423297 | 0.83 | PDGFRA (0.52) | KDRFLT3METMST1RPDGFRA | |
| SCHEMBL30646064 | 0.83 | PDGFRA (0.52) | KDRFLT3METMST1RPDGFRA | |
| SCHEMBL25130670 | 0.78 | KRAS (0.53) | METKRASSOS1RIPK2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |
| CN-111253385-A | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2020-06-09 | — | — | CN | disclosed |