Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 11/20 | 0.62 |
| ▸ | KDR | P35968 | 8/20 | 0.62 |
| ▸ | MET | P08581 | 5/20 | 0.51 |
| ▸ | MST1R | Q04912 | 3/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29111053 | 1.00 | PDGFRA (0.62) | PDGFRAKDRMETMST1RKIT | |
| SCHEMBL29111067 | 0.89 | PDGFRA (0.58) | PDGFRAKDRMETMST1RKIT | |
| SCHEMBL30646048 | 0.88 | PDGFRA (0.50) | PDGFRAKDRMETMST1RKIT | |
| SCHEMBL30646030 | 0.87 | ACHE (0.51) | PDGFRAKDRKITPDGFRB | |
| SCHEMBL29111054 | 0.87 | ACHE (0.51) | PDGFRAKDRKITPDGFRB | |
| SCHEMBL28428914 | 0.86 | PDGFRA (0.49) | PDGFRAKDRMETMST1RKIT | |
| SCHEMBL28427821 | 0.86 | MET (0.48) | PDGFRAKDRMETMST1RKIT | |
| SCHEMBL30646026 | 0.85 | PDGFRA (0.62) | PDGFRAKDRMETKITKRAS | |
| SCHEMBL29111060 | 0.85 | PDGFRA (0.62) | PDGFRAKDRMETKITKRAS | |
| SCHEMBL28420947 | 0.84 | KDR (0.51) | PDGFRAKDRMETMST1RKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |