SCHEMBL5823760

SCHEMBL5823760

Cc1ccc(Nc2ccccc2O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.60
GAA P10253 6/20 0.60
TDP1 Q9NUW8 1/20 0.60
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
HPGD P15428 3/20 0.56
CXCR2 P25025 3/20 0.50
TP53 P04637 2/20 0.49
LMNA P02545 1/20 0.49
NFKB1 P19838 1/20 0.49
HTT P42858 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
G6PD P11413 1/20 0.47
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30686692 1.00 MAPT (0.60) MAPTGAATDP1NPC1RAB9A
SCHEMBL17063545 0.98 HPGD (0.59) MAPTGAATDP1NPC1RAB9A
SCHEMBL1920750 0.89 CXCR2 (0.59) MAPTGAATDP1NPC1RAB9A
SCHEMBL7830951 0.88 NPSR1 (0.58) MAPTGAATDP1NPC1RAB9A
SCHEMBL1713014 0.84 MAPT (0.72) MAPTGAATDP1NPC1RAB9A
SCHEMBL1921886 0.83 CXCR2 (0.53) MAPTGAATDP1NPC1RAB9A
SCHEMBL6760764 0.83 MAPT (0.55) MAPTGAATDP1NPC1RAB9A
SCHEMBL11000813 0.83 CXCR2 (0.63) MAPTGAATDP1NPC1RAB9A
SCHEMBL29720861 0.82 CXCR2 (0.68) MAPTGAATDP1NPC1RAB9A
SCHEMBL1008928 0.82 CXCR2 (0.68) MAPTGAATDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117165127-A Sealing material for hydrogen production electrolytic tank and gasket structure thereof 镇江春环密封件集团有限公司 2023-12-05 CN claimed
CN-117165127-A Sealing material for hydrogen production electrolytic tank and gasket structure thereof 镇江春环密封件集团有限公司 2023-12-05 CN disclosed
US-20210024455-A1 COMPOUND WHICH INHIBITS TELOMERE-BINDING PROTEIN, AND TELOMERE-BINDING PROTEIN INHIBITOR CONTAINING SAME HIROSHIMA UNIVERSITY (JP) 2021-01-28 US disclosed
WO-2019181714-A1 COMPOUND WHICH INHIBITS TELOMERE-BINDING PROTEIN, AND TELOMERE-BINDING PROTEIN INHIBITOR CONTAINING SAME 国立大学法人広島大学 2019-09-26 WO disclosed
CN-104341395-B Novel azole compounds, process for their preparation and pharmaceutical compositions containing them 瑟维尔实验室 2017-07-04 CN disclosed
CN-106674196-A Pyrrole compounds, method of preparing same and pharmaceutical compositions containing them 法国施维雅药厂 2017-05-17 CN disclosed
CN-106674201-A Pyrrole compounds, method of preparing same and pharmaceutical compositions containing the compounds 法国施维雅药厂 2017-05-17 CN disclosed
WO-2006023435-A1 2-(AMINO OR SUBSTITUTED AMINO)-5, 6-SUBSTITUTED PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2006-03-02 WO disclosed
US-20040242891-A1 Production of keto acids CAMPBELL JONATHAN (GB) 2004-12-02 US disclosed
EP-1442009-A1 PRODUCTION OF KETO ACIDS Ciba SC Holding AG (CH) 2004-08-04 EP disclosed
EP-0853079-B1 Production of keto acids CIBA SC HOLDING AG (CH) 2002-06-05 EP disclosed
US-6296781-B1 APPLYING MIXTURE OF DISPERSANT, EMOLLIENT, EMULSIFIER, OXYGEN DEPLETER AND COMPETITOR, FREE RADICAL SCAVENGER, AND WATER BIOGENESIS ENTERPRISES, INC. 2001-10-02 US disclosed
EP-1115579-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION Ciba SC Holding AG (CH) 2001-07-18 EP disclosed
WO-2000026037-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-11 WO disclosed
WO-2000012318-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO disclosed
US-5942545-A Composition and method for treating penile erectile dysfunction MACROCHEM CORPORATION (US) 1999-08-24 US disclosed
US-5925787-A Production of keto acids CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-07-20 US disclosed
EP-0853079-A1 Production of keto acids Ciba SC Holding AG (CH) 1998-07-15 EP disclosed
US-4156682-A Fluoran compounds and recording sheet containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-05-29 US disclosed
US-4024157-A Fluoran compounds and recording sheet containing them SUMITOMO CHEMICAL COMPANY LIMITED (JA) 1977-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242891-A1 Production of keto acids PKLR, KHK, ME1 MAPT 2856/4885GAA 4000/4885TDP1 4681/4885
US-20210024455-A1 COMPOUND WHICH INHIBITS TELOMERE-BINDING PROTEIN, AND TELOMERE-BINDING PROTEIN INHIBITOR CONTAINING SAME TERF2IP, TERF2, POT1 MAPT 2067/4885GAA 4185/4885TDP1 289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.