Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686692 | 0.98 | MAPT (0.60) | HPGDGAAMAPTTDP1NPC1 | |
| SCHEMBL5823760 | 0.98 | MAPT (0.60) | HPGDGAAMAPTTDP1NPC1 | |
| SCHEMBL1920750 | 0.87 | CXCR2 (0.59) | HPGDGAAMAPTTDP1NPC1 | |
| SCHEMBL7830951 | 0.86 | NPSR1 (0.58) | HPGDGAAMAPTTDP1NPC1 | |
| SCHEMBL11000813 | 0.85 | CXCR2 (0.63) | HPGDGAAMAPTTDP1NPC1 | |
| SCHEMBL1713014 | 0.83 | MAPT (0.72) | HPGDGAAMAPTTDP1NPC1 | |
| SCHEMBL1921886 | 0.81 | CXCR2 (0.53) | HPGDGAAMAPTTDP1NPC1 | |
| SCHEMBL6760764 | 0.81 | MAPT (0.55) | HPGDGAAMAPTTDP1NPC1 | |
| SCHEMBL29720861 | 0.81 | CXCR2 (0.68) | HPGDGAAMAPTTDP1NPC1 | |
| SCHEMBL1008928 | 0.81 | CXCR2 (0.68) | HPGDGAAMAPTTDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900746-B1 | RUBBER COMPOSITION AND METHOD FOR LOW RESIN CROSSLINKING | MICHELIN & CIE (FR) | 2019-09-11 | — | — | EP | disclosed |
| US-9708459-B2 | Rubber composition and method for low resin crosslinking | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2017-07-18 | — | — | US | disclosed |
| US-20150252167-A1 | RUBBER COMPOSITION AND METHOD FOR LOW RESIN CROSSLINKING | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2015-09-10 | — | — | US | disclosed |