Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096567 | 0.80 | NLRP3 (0.59) | NLRP3ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL2096563 | 0.77 | NLRP3 (0.56) | NLRP3ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL9359788 | 0.76 | NLRP3 (0.78) | NLRP3ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL12467693 | 0.75 | ALDH1A1 (0.52) | NLRP3ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL24574915 | 0.74 | LCK (0.60) | NLRP3ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL30051979 | 0.73 | MAPT (0.67) | ALDH1A1L3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL4333871 | 0.73 | POLB (0.60) | NLRP3ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL6430240 | 0.73 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL10526068 | 0.73 | ALDH1A1 (0.56) | NLRP3ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL10524933 | 0.73 | NLRP3 (0.59) | NLRP3ALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111410666-B | Process for preparing sulfonamide compound | 苏州亚盛药业有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-111410666-A | Process for preparing sulfonamide compound | 苏州亚盛药业有限公司 | 2020-07-14 | — | — | CN | disclosed |