Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422730 | 0.73 | POLB (0.40) | ALDH1A1KMT2AHPGD | |
| SCHEMBL6882742 | 0.72 | LMNA (0.40) | NAAAALDH1A1HTTMEN1MAPT | |
| SCHEMBL28313149 | 0.72 | CXCR2 (0.44) | ALDH1A1HTTCA2MEN1MAPT | |
| SCHEMBL1834459 | 0.72 | LMNA (0.42) | NAAAALDH1A1HTTMEN1MAPT | |
| SCHEMBL6879939 | 0.71 | KCNH2 (0.42) | NAAAALDH1A1HTTMEN1MAPT | |
| SCHEMBL4630050 | 0.70 | ALDH1A1 (0.41) | NAAAALDH1A1HTTMEN1MAPT | |
| SCHEMBL1838977 | 0.70 | ALDH1A1 (0.44) | NAAAALDH1A1HTTMEN1MAPT | |
| SCHEMBL1836466 | 0.70 | ALDH1A1 (0.44) | NAAAALDH1A1HTTMEN1MAPT | |
| SCHEMBL1838702 | 0.70 | ALDH1A1 (0.44) | NAAAALDH1A1HTTMEN1MAPT | |
| SCHEMBL1840317 | 0.70 | ALDH1A1 (0.44) | NAAAALDH1A1HTTMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028521-B | 11-aryl-1, 4-benzoxazinoimidazoline compounds and preparation method and application thereof | 湖南科技大学 | 2020-07-14 | — | — | CN | disclosed |