Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422731 | 0.73 | NAAA (0.45) | ALDH1A1HPGDKMT2A | |
| SCHEMBL28313149 | 0.72 | CXCR2 (0.44) | NPC1RAB9AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL6884413 | 0.72 | TSHR (0.40) | POLBSMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL6884454 | 0.70 | POLB (0.42) | POLBSMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL6880364 | 0.70 | TSHR (0.41) | POLBSMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL6881722 | 0.69 | TSHR (0.44) | POLBSMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL6882773 | 0.69 | TSHR (0.37) | POLBTSHRGABRA1GABRB2ALDH1A1 | |
| SCHEMBL19954233 | 0.68 | POLB (0.62) | POLBTSHRALDH1A1GAAMAPK1 | |
| SCHEMBL6874442 | 0.68 | HTR1A (0.41) | POLBTSHRGABRA1GABRB2HTR1A | |
| SCHEMBL6884060 | 0.68 | TSHR (0.39) | TSHRGABRA1GABRB2ALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028521-B | 11-aryl-1, 4-benzoxazinoimidazoline compounds and preparation method and application thereof | 湖南科技大学 | 2020-07-14 | — | — | CN | disclosed |