Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | DDX3X | O00571 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281094 | 0.79 | KDM4E (0.38) | KDM4EL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL7036650 | 0.75 | CRHBP (0.49) | CXCR2KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL21851005 | 0.75 | CRHBP (0.49) | CXCR2KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL28422730 | 0.72 | POLB (0.40) | KDM4EL3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL28422731 | 0.72 | NAAA (0.45) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL10333062 | 0.70 | ALDH1A1 (0.42) | KDM4EL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL387883 | 0.70 | ALDH1A1 (0.42) | KDM4EL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL4174589 | 0.69 | ALDH1A1 (0.39) | CXCR2KDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL9297141 | 0.69 | KDM4E (0.44) | KDM4EL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL6821782 | 0.69 | ALDH1A1 (0.39) | CXCR2KDM4EL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028521-B | 11-aryl-1, 4-benzoxazinoimidazoline compounds and preparation method and application thereof | 湖南科技大学 | 2020-07-14 | — | — | CN | disclosed |
| CN-110028521-A | 11- aryl -1,4- benzoxazinone and imidazolines and its preparation method and application | 湖南科技大学 | 2019-07-19 | — | — | CN | disclosed |