Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 6/20 | 0.42 |
| ▸ | CTSL | P07711 | 6/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.38 |
| ▸ | FEN1 | P39748 | 5/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411537 | 0.90 | LMNA (0.44) | CTSVCTSLHTR1ASLC6A2SLC6A4 | |
| SCHEMBL28415410 | 0.78 | CTSV (0.38) | CTSVCTSLALDH1A1LMNAPOLB | |
| SCHEMBL29858779 | 0.73 | LMNA (0.44) | CTSVCTSLHTR1ASLC6A2SLC6A4 | |
| SCHEMBL2893296 | 0.72 | GRIN2D (0.47) | CTSVCTSLMGMT | |
| SCHEMBL6762897 | 0.72 | CTSV (0.52) | CTSVCTSLALDH1A1POLB | |
| SCHEMBL28416297 | 0.72 | LMNA (0.47) | CTSVCTSLALDH1A1LMNAPOLB | |
| SCHEMBL7552230 | 0.71 | MGMT (0.49) | HPDMGMT | |
| SCHEMBL31055978 | 0.70 | CTSV (0.41) | CTSVCTSLHTR1ASLC6A2SLC6A4 | |
| SCHEMBL12253970 | 0.70 | PTPN1 (0.47) | CTSVCTSLMGMTSMN1; SMN2 | |
| SCHEMBL5466233 | 0.70 | PKM (0.57) | CTSVCTSLMRGPRX4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196816-B | Seven-membered ring compound and application thereof in preventing and treating diabetes and metabolic syndrome | 中国科学院上海药物研究所 | 2022-11-04 | — | — | CN | disclosed |
| CN-111196816-A | Seven-membered ring compound and application thereof in preventing and treating diabetes and metabolic syndrome | 中国科学院上海药物研究所 | 2020-05-26 | — | — | CN | disclosed |