SCHEMBL962950

SCHEMBL962950

O=C1C=CC(=O)N1c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 1.00
FAAH O00519 5/20 0.75
HSP90AA1 P07900 2/20 0.60
TDP1 Q9NUW8 2/20 0.60
PKM P14618 1/20 0.60
MAPK1 P28482 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
BCHE P06276 1/20 0.54
DDAH1 O94760 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
ELANE P08246 1/20 0.54
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
CCR6 P51684 1/20 0.52
CACNA1B Q00975 1/20 0.52
APBA1 Q02410 1/20 0.52
APOBEC3G Q9HC16 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Anhydride SCHEMBL8720485 0.88 MGLL (0.77) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL95324 0.87 MGLL (1.00) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL28883435 0.86 MGLL (0.74) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL21801270 0.85 MGLL (0.73) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL19511560 0.79 MGLL (0.83) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL21630074 0.79 MGLL (0.83) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL1321309 0.79 MGLL (0.83) MGLLFAAHHSP90AA1TDP1PKM
Pyrazole SCHEMBL28098996 0.79 MGLL (0.62) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL3171879 0.77 MGLL (0.62) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL9839165 0.77 MGLL (0.79) MGLLFAAHHSP90AA1TDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12358943-B1 Method of synthesizing testosterone-based thiazolidinone derivatives IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-07-15 US claimed
CN-115398219-B Capillary gel electrophoresis and its use in complex biomolecules 阿瑞斯贸易股份公司 2025-04-01 CN claimed
CN-117854847-B Production process of anti-aging enameled rectangular copper wire 江苏东恒光电有限公司 2024-08-27 CN claimed
CN-117854847-A Production process of anti-aging enameled rectangular copper wire 江苏东恒光电有限公司 2024-04-09 CN claimed
US-11708443-B2 Method of preparing graft copolymer LG CHEM, LTD. (KR) 2023-07-25 US claimed
CN-111971317-B Process for the preparation of graft copolymers 株式会社LG化学 2023-07-07 CN claimed
CN-115591418-B Diaphragm for trapping dioxin and preparation method thereof 佛山(华南)新材料研究院 2023-06-09 CN claimed
EP-3763757-B1 METHOD OF PREPARING GRAFT POLYMER LG CHEMICAL LTD (KR) 2023-06-07 EP claimed
CN-113546683-B Application of covalent organic framework material based on porphyrin in photocatalytic oxidation cyclization reaction 山东师范大学 2023-04-28 CN claimed
CN-115591418-A Membrane for trapping dioxin and preparation method thereof 佛山(华南)新材料研究院(CN) 2023-01-13 CN claimed
EP-0247257-A1 Polymer composition containing polycarbonate, a styrenic/maleimide/cyclic anhydride terpolymer and a terpolymer grafted to a polymer matrix ARCO Chemical Technology, L.P. (US) 1987-12-02 EP claimed
EP-0220909-A2 Thermodynamically miscible polymer composition ARCO Chemical Technology, L.P. (US) 1987-05-06 EP claimed
EP-0196872-A2 Molding composition containing functionalised thermoplastic rubber and method ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-10-08 EP claimed
EP-0194384-A1 Thermodynamically miscible polymer compostions ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-09-17 EP claimed
US-4605700-A OLEFIN-MALEIMIDE COPOLYMER AND ACRYLONITRILE-VINYL AROMATIC COPOLYMER BLEND HAVING A SINGLE GLASS TRANSITION TEMPERATURE; MOLDINGS ATLANTIC RICHFIELD COMPANY (US) 1986-08-12 US claimed
US-4588774-A MOLDING MATERIALS, MALEIMIDE MONOMER, GRAFTED SYNTHETIC RUBBERS ATLANTIC RICHFIELD COMPANY (US) 1986-05-13 US claimed
US-4497928-A Moldable polyblend containing poly(arylene sulfide) ATLANTIC RICHFIELD COMPANY (US) 1985-02-05 US claimed
US-4342860-A AN UNSATUREATED IMIDE IS USED WITH A DI OR POLYISOCYANATE TO FORM A POLYIMIDE POLYMER RHONE-POULENC INDUSTRIES (FR) 1982-08-03 US claimed
US-4342861-A AN UNSATURATGED IMIDE AND A DI OR POLYISOCYANATE GO TO MAKE UP A POLYIMIDE POLYMER WHICH ALSO CONTAINS REPEATING AMIDE GROUPS RHONE-POULENC INDUSTRIES (FR) 1982-08-03 US claimed
US-4302572-A MOLDING MATERIALS; COATINGS; HEAT RESISTANCE; THIN FILMS RHONE-POULENC INDUSTRIES (FR) 1981-11-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358943-B1 Method of synthesizing testosterone-based thiazolidinone derivatives ERG28, CYP17A1, AR MGLL 2582/4885FAAH 4856/4885HSP90AA1 1501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.