Maleic Anhydride

Maleic Anhydride

SCHEMBL8720485

O=C1C=CC(=O)N1c1ccc(Cl)cc1.O=C1C=CC(=O)O1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 0.77
FAAH O00519 5/20 0.58
HSP90AA1 P07900 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
PKM P14618 1/20 0.48
MAPK1 P28482 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
DDAH1 O94760 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ELANE P08246 1/20 0.44
BCHE P06276 1/20 0.44
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
CCR6 P51684 1/20 0.43
CACNA1B Q00975 1/20 0.43
APBA1 Q02410 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL962950 0.88 MGLL (1.00) MGLLFAAHHSP90AA1TDP1PKM
Maleic Anhydride SCHEMBL17534910 0.80 MGLL (0.75) MGLLFAAHHSP90AA1TDP1PKM
Maleic Anhydride SCHEMBL8720551 0.77 DDAH1 (0.79) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL95324 0.76 MGLL (1.00) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL28883435 0.76 MGLL (0.74) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL21801270 0.74 MGLL (0.73) MGLLFAAHHSP90AA1TDP1PKM
Maleic Anhydride SCHEMBL8722603 0.72 GLA (0.56) MGLLFAAHHSP90AA1TDP1PKM
Maleic Anhydride SCHEMBL27779007 0.71 CES2 (0.48) TDP1NPSR1MEN1KMT2ABCHE
SCHEMBL7772704 0.69 MGLL (0.65) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL19511560 0.69 MGLL (0.83) MGLLFAAHHSP90AA1TDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830430-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF Jotun A/S (NO) 1998-03-25 EP disclosed
WO-1996041841-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN A/S (NO) 1996-12-27 WO disclosed