Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646052 | 0.89 | SOS1 (0.44) | PDGFRBSOS1NSD2RAB9AMEN1 | |
| SCHEMBL28423264 | 0.85 | SOS1 (0.41) | SOS1NSD2RAB9AMEN1KMT2A | |
| SCHEMBL29111070 | 0.85 | SOS1 (0.39) | PDGFRAPDGFRBSOS1NSD2MET | |
| SCHEMBL29111053 | 0.83 | PDGFRA (0.62) | PDGFRAKDRPDGFRBKITSOS1 | |
| SCHEMBL30646019 | 0.83 | PDGFRA (0.62) | PDGFRAKDRPDGFRBKITSOS1 | |
| SCHEMBL30646030 | 0.79 | ACHE (0.51) | PDGFRAKDRPDGFRBKITFLT3 | |
| SCHEMBL29111054 | 0.79 | ACHE (0.51) | PDGFRAKDRPDGFRBKITFLT3 | |
| SCHEMBL28425023 | 0.77 | CCNC (0.48) | PDGFRAKDRGCKRAB9AEGFR | |
| SCHEMBL29111067 | 0.77 | PDGFRA (0.58) | PDGFRAKDRKITMET | |
| SCHEMBL28425273 | 0.72 | CHEK2 (0.39) | GCKRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |
| CN-111253385-A | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2020-06-09 | — | — | CN | disclosed |