Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29111070 | 0.89 | SOS1 (0.39) | SOS1NSD2PDGFRBEGFRERBB2 | |
| SCHEMBL28423264 | 0.89 | SOS1 (0.41) | SOS1NSD2RAB9AMEN1KMT2A | |
| SCHEMBL28425382 | 0.89 | PDGFRA (0.44) | SOS1NSD2PDGFRBEGFRERBB2 | |
| SCHEMBL30646048 | 0.82 | PDGFRA (0.50) | SOS1PDGFRB | |
| SCHEMBL28428914 | 0.74 | PDGFRA (0.49) | SOS1PDGFRB | |
| SCHEMBL28423297 | 0.72 | PDGFRA (0.52) | — | |
| SCHEMBL30646064 | 0.72 | PDGFRA (0.52) | — | |
| SCHEMBL28420947 | 0.72 | KDR (0.51) | SOS1PDGFRBEGFRERBB2 | |
| SCHEMBL28427821 | 0.71 | MET (0.48) | SOS1PDGFRB | |
| SCHEMBL30646019 | 0.71 | PDGFRA (0.62) | SOS1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253385-B | Heterocyclic compound, preparation method and application | 遵义医科大学珠海校区 | 2023-11-24 | — | — | CN | disclosed |