Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421040 | 0.86 | ALDH1A1 (0.53) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL28631610 | 0.80 | NPC1 (0.48) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL543263 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL29107093 | 0.71 | PPID (0.53) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL3126004 | 0.71 | NPC1 (0.70) | SMN1; SMN2NPC1HPGDTDP1GAA | |
| SCHEMBL1421071 | 0.71 | L3MBTL1 (0.42) | SMN1; SMN2HPGDALDH1A1LMNAATM | |
| SCHEMBL28109095 | 0.70 | NPC1 (0.50) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL29107114 | 0.70 | PPID (0.55) | SMN1; SMN2ALDH1A1GAAPOLB | |
| SCHEMBL10108244 | 0.69 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KMT2AHTT | |
| SCHEMBL28861089 | 0.69 | NPC1 (0.44) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428720-B | Substituted aminotriazoles as inhibitors of acid mammalian chitinase | 昂科艾伦迪治疗法股份公司 | 2020-06-30 | — | — | CN | disclosed |