Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625455 | 0.88 | KDM4E (0.49) | NPC1SMN1; SMN2GAATPSAB1TPSD1 | |
| SCHEMBL28923423 | 0.86 | CNR1 (0.51) | NPC1SMN1; SMN2HPGDGAACNR1 | |
| SCHEMBL28640398 | 0.86 | ALDH1A1 (0.49) | NPC1SMN1; SMN2HPGDGAAALDH1A1 | |
| SCHEMBL28109095 | 0.86 | NPC1 (0.50) | NPC1SMN1; SMN2HPGDTPSAB1TPSD1 | |
| SCHEMBL28630343 | 0.84 | GLA (0.58) | NPC1SMN1; SMN2GAAALDH1A1RAB9A | |
| SCHEMBL28625023 | 0.83 | CYP3A4 (0.47) | SMN1; SMN2HPGDGAATPSAB1TPSD1 | |
| SCHEMBL28622914 | 0.80 | CES2 (0.52) | NPC1SMN1; SMN2HPGDGAATPSAB1 | |
| SCHEMBL28426547 | 0.80 | SMN1; SMN2 (0.52) | NPC1SMN1; SMN2HPGDGAAALDH1A1 | |
| SCHEMBL27875350 | 0.78 | HPGD (0.49) | NPC1SMN1; SMN2HPGDALDH1A1RAB9A | |
| SCHEMBL2021427 | 0.75 | FPR2 (0.58) | NPC1SMN1; SMN2GAAFPR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641878-B | DIPROVOCIM: effective TLR agonist | 斯克里普斯研究学院 | 2021-09-14 | — | — | CN | disclosed |