Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262770 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AMEN1CYP1A2TSHR | |
| SCHEMBL11250171 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AMEN1CYP1A2TSHR | |
| SCHEMBL11250168 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AMEN1CYP1A2TSHR | |
| SCHEMBL11254260 | 0.77 | HSD17B10 (0.49) | SMN1; SMN2KMT2AMEN1CYP1A2TSHR | |
| SCHEMBL28427552 | 0.75 | TARBP2 (0.46) | SMN1; SMN2KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL2025252 | 0.73 | LMNA (0.57) | SMN1; SMN2KMT2AMEN1CYP1A2TSHR | |
| SCHEMBL11272379 | 0.73 | ALDH1A1 (0.39) | SMN1; SMN2KMT2AMEN1CYP1A2TSHR | |
| SCHEMBL11272377 | 0.73 | ALDH1A1 (0.39) | SMN1; SMN2KMT2AMEN1CYP1A2TSHR | |
| SCHEMBL11251471 | 0.72 | ALDH1A1 (0.41) | SMN1; SMN2KMT2AMEN1CYP1A2TSHR | |
| SCHEMBL28429182 | 0.72 | MAPT (0.67) | KMT2AMEN1KDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349674-A | Quinoalinyl esters of carbamimidothioic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-14 | — | — | US | claimed |
| US-4349674-A | Quinoalinyl esters of carbamimidothioic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |