Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048831 | 0.78 | SLC6A3 (0.37) | SLC6A3SLC6A4SLC6A2SIGMAR1 | |
| SCHEMBL7690230 | 0.76 | MEN1 (0.44) | SLC6A3SLC6A4SLC6A2SIGMAR1 | |
| SCHEMBL8743740 | 0.75 | LIPG (0.44) | SLC6A3SLC6A4SLC6A2SIGMAR1OPRM1 | |
| SCHEMBL28601598 | 0.72 | SLC6A2 (0.43) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL8155610 | 0.62 | CNR2 (0.39) | SLC6A3SLC6A4SLC6A2OPRM1OPRK1 | |
| SCHEMBL17252581 | 0.61 | PGR (0.35) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6803384 | 0.61 | SLC6A3 (0.62) | SLC6A3SLC6A4SLC6A2DPP4 | |
| SCHEMBL28433943 | 0.61 | HDAC4 (0.38) | SLC6A4SIGMAR1OPRM1OPRK1OPRL1 | |
| SCHEMBL28428231 | 0.61 | CEL (0.34) | SIGMAR1 | |
| SCHEMBL28932566 | 0.60 | CNR2 (0.37) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111440053-A | Industrial production method of cyclopropylmethyl cyclohexyl difluorobiphenyl compounds | 西安瑞联新材料股份有限公司 | 2020-07-24 | — | — | CN | disclosed |