Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851466 | 0.95 | THRB (0.33) | LMNAHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL11448242 | 0.81 | TDP1 (0.33) | — | |
| SCHEMBL35565 | 0.81 | THRB (0.42) | LMNAHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL10571256 | 0.81 | THRB (0.42) | LMNAHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL35363 | 0.81 | THRB (0.42) | LMNAHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL11289157 | 0.81 | THRB (0.42) | LMNAHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL11170048 | 0.81 | THRB (0.42) | LMNAHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL11441821 | 0.81 | THRB (0.42) | LMNAHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL35803 | 0.81 | THRB (0.42) | LMNAHSD17B10TSHRALDH1A1MEN1 | |
| SCHEMBL10569638 | 0.79 | NOS3 (0.44) | LMNAHSD17B10TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111318718-B | Gold nano assembly with sensitization tumor radiotherapy and preparation method and application thereof | 中国科学技术大学 | 2021-10-19 | — | — | CN | claimed |
| CN-111318718-A | Gold nano assembly with sensitization tumor radiotherapy and preparation method and application thereof | 中国科学技术大学 | 2020-06-23 | — | — | CN | claimed |
| CN-111318718-B | Gold nano assembly with sensitization tumor radiotherapy and preparation method and application thereof | 中国科学技术大学 | 2021-10-19 | — | — | CN | disclosed |
| CN-111318718-A | Gold nano assembly with sensitization tumor radiotherapy and preparation method and application thereof | 中国科学技术大学 | 2020-06-23 | — | — | CN | disclosed |