SCHEMBL851466

SCHEMBL851466

CCCCCCCCCCCCSC(=S)SCC#N

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CES2 O00748 1/20 0.33
GMNN O75496 1/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
BLM P54132 1/20 0.33
ACHE P22303 3/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
NAAA Q02083 1/20 0.32
MGLL Q99685 1/20 0.32
EPHX1 P07099 1/20 0.31
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL28428294 0.95 LMNA (0.35) THRBTSHRHSD17B10CES2GMNN
SCHEMBL11448242 0.86 TDP1 (0.33) NOS3NOS1NOS2
SCHEMBL11289157 0.85 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL10571256 0.85 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL35363 0.85 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL35565 0.85 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL11170048 0.85 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL11441821 0.85 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL35803 0.85 THRB (0.42) THRBTSHRHSD17B10CES2GMNN
SCHEMBL10569638 0.83 NOS3 (0.44) THRBTSHRHSD17B10CES2GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
CN-120158013-A Transparent fluororesin with high stability, and preparation method and application thereof 四川道弘新材料股份有限公司 2025-06-17 CN claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
CN-118878726-A Polystyrene resin and preparation method thereof 江苏嘉琪发化工有限公司 2024-11-01 CN claimed
CN-118184840-A Polymeric ionic liquid and preparation method and application thereof 中国科学院过程工程研究所 2024-06-14 CN claimed
CN-117510724-A Nitrile rubber emulsion slurry and preparation method thereof 河北金力新能源科技股份有限公司 2024-02-06 CN claimed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US claimed
US-11834383-B2 Energetic feedstock for additive manufacturing LYNNTECH, INC. (US) 2023-12-05 US claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
CN-108503746-B Preparation and application of water-soluble 3D printing support material 台州学院 2021-02-09 CN claimed
CN-111318718-A Gold nano assembly with sensitization tumor radiotherapy and preparation method and application thereof 中国科学技术大学 2020-06-23 CN claimed
WO-2018140977-A1 REACTIONS ENABLED BY THERMORESPONSIVE AND PHOTORESPONSIVE GELS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-08-02 WO claimed
US-9771500-B2 Sealant composition for electronic device HENKEL AG & CO. KGAA (DE) 2017-09-26 US claimed
US-20160177148-A1 SEALANT COMPOSITION FOR ELECTRONIC DEVICE HENKEL AG & CO. KGAA (DE) 2016-06-23 US claimed
EP-2432808-B1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2015-10-21 EP claimed
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US claimed
US-7408013-B2 Low-polydispersity photoimageable polymers and photoresists and processes for microlithography COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AT) 2008-08-05 US claimed
US-20070123729-A1 Synthesis of trithiocarbonates E. I. DU PONT DE NEMOURS AND COMPANY 2007-05-31 US claimed
US-20050112495-A1 Low-polydispersity photoimageable polymers and photoresists and processes for microlithography COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-05-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA THRB 2167/4885TSHR 2876/4885HSD17B10 2033/4885
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS VCL, MACF1, CFL1 THRB 4456/4885TSHR 3589/4885HSD17B10 3175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.