Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | EYA2 | O00167 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4868996 | 0.97 | TSHR (0.35) | TDP1EYA2APPACELMNA | |
| SCHEMBL19615405 | 0.86 | TDP1 (0.32) | TDP1EYA2APPACELMNA | |
| SCHEMBL3753416 | 0.84 | CAMK2A (0.41) | — | |
| SCHEMBL9280314 | 0.84 | GPR84 (0.48) | TDP1APPTSHRALOX15SLC22A6 | |
| SCHEMBL537217 | 0.84 | LMNA (0.48) | LMNATSHRCHRM2ALOX15SLC6A2 | |
| SCHEMBL3230784 | 0.84 | EYA2 (0.31) | TDP1EYA2APPACETSHR | |
| SCHEMBL3756453 | 0.82 | — | — | |
| SCHEMBL9051005 | 0.82 | TSHR (0.33) | TDP1EYA2APPACELMNA | |
| SCHEMBL31662731 | 0.81 | TDP1 (0.35) | TDP1EYA2APPACELMNA | |
| Magnesium SCHEMBL3108011 | 0.79 | TDP1 (0.33) | TDP1EYA2APPACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303122-A | Pomalidomide derivative and application thereof | 南方医科大学 | 2020-06-19 | — | — | CN | claimed |
| CN-111303122-A | Pomalidomide derivative and application thereof | 南方医科大学 | 2020-06-19 | — | — | CN | disclosed |
| CN-111303122-A | Pomalidomide derivative and application thereof | 南方医科大学 | 2020-06-19 | — | — | CN | disclosed |