SCHEMBL28428630

SCHEMBL28428630

CC(CS(=O)(=O)O)C(CCO[Si](C(C)C)(C(C)C)C(C)C)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GMNN O75496 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
PMP22 Q01453 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.33
KCNA5 P22460 6/20 0.32
TAAR1 Q96RJ0 1/20 0.31
SRC P12931 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16756832 0.82 SLC6A2 (0.38) KMT2AKDM4EALDH1A1LMNAMEN1
SCHEMBL28423121 0.79 TRPA1 (0.44) KMT2AKDM4EGMNNALDH1A1LMNA
SCHEMBL16757087 0.77 TAAR1 (0.32) KMT2AKDM4EGMNNALDH1A1LMNA
SCHEMBL19666973 0.72 RIPK1 (0.47) KDM4EALDH1A1LMNA
SCHEMBL17835608 0.72 RIPK1 (0.47) KDM4EALDH1A1LMNA
SCHEMBL28423098 0.72 ALDH1A1 (0.41) KMT2AKDM4EGMNNALDH1A1LMNA
SCHEMBL9285250 0.69 ALDH1A1 (0.54) KMT2AKDM4EGMNNALDH1A1LMNA
SCHEMBL5217546 0.66 TAAR1 (0.48) KMT2AKDM4EGMNNALDH1A1LMNA
SCHEMBL5217923 0.66 TAAR1 (0.48) KMT2AKDM4EGMNNALDH1A1LMNA
SCHEMBL5217555 0.66 TAAR1 (0.48) KMT2AKDM4EGMNNALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107011168-B Synthesis intermediates of cytosines and synthesis intermediates of thionucleosides 富士胶片株式会社 2020-06-09 CN disclosed