Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319165 | 0.85 | MIF (0.57) | MIFMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL28048765 | 0.83 | ALDH1A1 (0.77) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL27974961 | 0.83 | ALDH1A1 (0.62) | MIFMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL3494129 | 0.83 | MAPT (0.73) | MIFPPARGPPARDPPARAMAPT | |
| SCHEMBL3959661 | 0.78 | MIF (0.69) | MIFPPARGPPARDPPARAMAPT | |
| Isoflavone SCHEMBL8028 | 0.75 | ALDH1A1 (0.66) | MIFMAPTSMN1; SMN2ALDH1A1NPC1 | |
| Isoflavone SCHEMBL6290885 | 0.75 | ALDH1A1 (0.66) | MIFMAPTSMN1; SMN2ALDH1A1NPC1 | |
| Isoflavone SCHEMBL6542422 | 0.75 | ALDH1A1 (0.66) | MIFMAPTSMN1; SMN2ALDH1A1NPC1 | |
| Isoflavone SCHEMBL31264756 | 0.75 | ALDH1A1 (0.66) | MIFMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8602 | 0.75 | MIF (0.61) | MIFPPARGPPARDPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116492331-A | Application of isoflavone in preparing medicines for resisting vascular endothelial cell injury | 湖南中医药大学 | 2023-07-28 | — | — | CN | claimed |
| CN-111249271-A | Medicament for treating diabetes and preparation method and application thereof | 中南民族大学 | 2020-06-09 | — | — | CN | claimed |
| CN-116492331-A | Application of isoflavone in preparing medicines for resisting vascular endothelial cell injury | 湖南中医药大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-116492331-A | Application of isoflavone in preparing medicines for resisting vascular endothelial cell injury | 湖南中医药大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-111249271-A | Medicament for treating diabetes and preparation method and application thereof | 中南民族大学 | 2020-06-09 | — | — | CN | disclosed |