SCHEMBL28429201

SCHEMBL28429201

C=C(C)C(=O)OCCNS(=O)(=O)F

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3243694 0.84 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9418366 0.84 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL12330291 0.83 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3256380 0.82 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL14769572 0.81 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL217339 0.81 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL15836509 0.79 THRB (0.40) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28366360 0.77 TSHR (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL11418593 0.77 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2632780 0.77 CA1 (0.40) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109880017-B Fluorine-containing polymer binder, preparation method thereof and application thereof in silicon-based electrode lithium ion battery 浙江大学 2020-07-21 CN disclosed