Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430488 | 0.92 | CA1 (0.49) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL29114525 | 0.84 | ALDH1A1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5196180 | 0.84 | CA1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6940566 | 0.83 | ALDH1A1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28431416 | 0.83 | MMP2 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28435626 | 0.82 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28432684 | 0.82 | KMT2A (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28430621 | 0.78 | CA2 (0.57) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL23852661 | 0.77 | KMT2A (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28431417 | 0.76 | MMP9 (0.54) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111087338-B | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2021-03-02 | — | — | CN | claimed |
| CN-111087338-A | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2020-05-01 | — | — | CN | claimed |
| CN-111087338-B | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-111087338-A | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2020-05-01 | — | — | CN | disclosed |