SCHEMBL28433339

SCHEMBL28433339

CCCOC(=O)C=Cc1ccc(OC)cc1.[SiH4]

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.70
TDP1 Q9NUW8 2/20 0.70
SMN1; SMN2 Q16637 1/20 0.65
ALOX5 P09917 1/20 0.63
APP P05067 2/20 0.61
GSK3B P49841 1/20 0.59
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
MAPT P10636 1/20 0.58
F3 P13726 2/20 0.58
THRB P10828 1/20 0.57
ATM Q13315 1/20 0.57
KDM4E B2RXH2 1/20 0.56
CASP3 P42574 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
GAA P10253 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC2 Q92769 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39355 0.98 LMNA (0.72) LMNATDP1SMN1; SMN2ALOX5APP
SCHEMBL39354 0.98 LMNA (0.72) LMNATDP1SMN1; SMN2ALOX5APP
Propionic Acid SCHEMBL27993336 0.93 LMNA (0.65) LMNATDP1SMN1; SMN2ALOX5APP
SCHEMBL4623831 0.91 LMNA (0.73) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL1614879 0.91 LMNA (0.73) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL20943451 0.89 LMNA (0.68) LMNATDP1SMN1; SMN2ALOX5APP
Cinnamic Acid SCHEMBL20555427 0.89 THRB (0.64) LMNATDP1SMN1; SMN2ALOX5APP
SCHEMBL1614552 0.88 LMNA (0.70) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL1614553 0.88 LMNA (0.70) LMNATDP1SMN1; SMN2APPGSK3B
SCHEMBL59457 0.87 LMNA (0.68) LMNATDP1SMN1; SMN2APPGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111471362-B Ultraviolet ray filters base plate and disinfection stick 胡克海 2021-11-09 CN disclosed
CN-111471362-A Ultraviolet ray filters base plate and disinfection stick 胡克海 2020-07-31 CN disclosed