Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.58 |
| ▸ | BCL6 | P41182 | 2/20 | 0.53 |
| ▸ | BCOR | Q6W2J9 | 2/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25875012 | 0.85 | KIF11 (0.65) | KIF11BCL6BCORCRBNPKM | |
| SCHEMBL22159513 | 0.81 | CRBN (0.68) | KIF11BCL6BCORCRBN | |
| SCHEMBL22159539 | 0.81 | CRBN (0.53) | KIF11BCL6BCORCRBNULK1 | |
| SCHEMBL5543910 | 0.74 | NPC1 (0.55) | KIF11CRBNPKM | |
| SCHEMBL16208459 | 0.74 | KIF11 (1.00) | KIF11BCL6BCORCRBNPKM | |
| SCHEMBL17545219 | 0.70 | ULK1 (0.60) | KIF11BCL6BCORULK1 | |
| SCHEMBL23249972 | 0.70 | BCL6 (0.84) | KIF11BCL6BCORCRBNPKM | |
| SCHEMBL29874183 | 0.70 | BCL6 (0.84) | KIF11BCL6BCORCRBNPKM | |
| SCHEMBL25875011 | 0.69 | MAPK14 (0.59) | KIF11CRBNTNIKULK1 | |
| SCHEMBL16208480 | 0.69 | KIF11 (0.72) | KIF11CRBNTNIKPKMULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278816-A | Dihydroquinolinones | C4医药公司 | 2020-06-12 | — | — | CN | disclosed |