Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28433794 | 0.88 | CA2 (0.36) | TSHRCA2CA12CA14 | |
| SCHEMBL8843778 | 0.83 | PHF8 (0.42) | TSHRCA12CA14 | |
| SCHEMBL28438678 | 0.80 | LDHA (0.33) | LDHASRRTSHR | |
| SCHEMBL15523475 | 0.79 | MGAM (0.33) | TSHRCA2CA12CA14 | |
| SCHEMBL28430592 | 0.77 | CA1 (0.38) | LDHASRRCA2 | |
| SCHEMBL31547597 | 0.76 | ALDH1A1 (0.46) | TSHRCA2CA12CA14 | |
| SCHEMBL28431435 | 0.75 | KDM4E (0.33) | — | |
| SCHEMBL5492894 | 0.71 | LDHA (0.38) | LDHASRRTSHRCA12CA14 | |
| SCHEMBL28549611 | 0.71 | GAA (0.46) | TSHRCA2CA12CA14 | |
| SCHEMBL14714892 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111087338-B | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2021-03-02 | — | — | CN | claimed |
| CN-111087338-A | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2020-05-01 | — | — | CN | claimed |
| CN-111087338-B | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-111087338-A | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2020-05-01 | — | — | CN | disclosed |