SCHEMBL5492894

SCHEMBL5492894

CS(=O)(=O)OC(=O)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
TSHR P16473 3/20 0.34
CA12 O43570 1/20 0.32
CA14 Q9ULX7 1/20 0.32
POLB P06746 1/20 0.32
FFAR3 O14843 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28430222 0.87 MGAM (0.39) TSHRCA12CA14USP2
SCHEMBL13155761 0.80 MGAM (0.52) TSHRCA12CA14USP2
SCHEMBL28033987 0.79 LDHA (0.42) LDHASRRTSHRCA12CA14
SCHEMBL11095630 0.78 PHF8 (0.46) TSHRFFAR3
SCHEMBL28431006 0.78 ALOX15 (0.38)
SCHEMBL28930135 0.76 PHF8 (0.45) TSHRFFAR3
SCHEMBL27631242 0.76
SCHEMBL7633682 0.76 TSHR (0.43) TSHRCA12CA14USP2
Hydrochloric Acid SCHEMBL11346543 0.74 USP2 (0.33) TSHRCA12CA14USP2
SCHEMBL576706 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106470974-B For treating the compound of virus infection 韩国巴斯德研究所 2019-07-16 CN disclosed
US-20130101684-A1 Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste CHROMOCELL CORPORATION (US) 2013-04-25 US disclosed
WO-2007107008-A1 COMPOUNDS AND COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF DISORDERS OF FAT METABOLISM AND OBESITY INNODIA INC. (CA) 2007-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130101684-A1 Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste TAS2R5, TAS2R20, TAS2R10 LDHA 4599/4885SRR 2991/4885TSHR 2181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.