Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24306335 | 0.79 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL951764 | 0.78 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL1811528 | 0.78 | ALOX5AP (0.33) | DGAT1NPC1 | |
| SCHEMBL23939802 | 0.78 | DGAT1 (0.32) | DGAT1NPC1 | |
| SCHEMBL29961918 | 0.78 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL949085 | 0.77 | ALDH1A1 (0.43) | DGAT1 | |
| SCHEMBL20272451 | 0.77 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL953734 | 0.76 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL16387217 | 0.76 | NPC1 (0.36) | DGAT1NPC1 | |
| SCHEMBL18863096 | 0.76 | SMN1; SMN2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111556871-B | 1H-pyrazolo [4,3-b ] pyridines as PDE1 inhibitors | H.隆德贝克有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-111465410-B | Combination therapy comprising administration of 1H-pyrazolo [4,3-B ] pyridine | H.隆德贝克有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-111526890-B | Combination therapy comprising administration of 1H-pyrazolo [4,3-B ] pyridine | H.隆德贝克有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-109311872-B | 1H-pyrazolo [4,3-b ] pyridines as PDE1 inhibitors | H.隆德贝克有限公司 | 2021-08-20 | — | — | CN | disclosed |
| CN-111556871-A | 1H-pyrazolo [4,3-b ] pyridines as PDE1 inhibitors | H.隆德贝克有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-111526890-A | Combination therapy comprising administration of 1H-pyrazolo [4,3-B ] pyridine | H.隆德贝克有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-111465410-A | Combination therapy comprising administration of 1H-pyrazolo [4,3-B ] pyridine | H.隆德贝克有限公司 | 2020-07-28 | — | — | CN | disclosed |